Schizophrenia Paper - 990 Words

Schizophrenia is a complex and highly debilitating mental illness that we are currently unable to treat in any way that guarantees success or return to previous function. It affects around 1% of the population and is associated with a thirteen-fold increase in the likelihood of suicide, so its effective control is paramount (Gogos et al., 2015). There have been several hypotheses as to the cause of schizophrenia. Many link genetic and environmental factors, and dysregulations of neurotransmitters dopamine, glutamate, and serotonin (Egbujo, Sinclair, Hahn, 2016). The dopamine hypothesis currently suggests that hyperactive dopamine transmission in the basal ganglia leads to psychosis and underactive dopamine transmission in the prefrontal†¦show more content†¦A medication with these properties would be difficult to develop, but potentially quite beneficial and efficacious. Literature Review It is hypothesized that dysregulation at the presynaptic terminals can impact functionality at post-synaptic terminals and alter dopamine and glutamate levels (Egbujo et al., 2016). This impact on dopamine and glutamate could be the precursor to the altered functional connectivity seen in schizophrenia (Egbujo et al., 2016). The molecular processes that underlie this process include presynaptic SNARE proteins, synaptic membrane proteins, synapsins, syntaxin-1, synaptobrevin, and complexins (Egbujo et al., 2016). In many cases, these proteins are under or over expressed in certain areas of the brain crucial to schizophrenia (Egbujo et al., 2016). The overall mechanism operating efficiently would involve neurotransmitter recruitment and concentration within vesicles, targeting the pooled vesicles to the presynaptic terminal, and vesicle exocytosis, endocytosis, and recycling (Egbujo et al., 2016). The previously mentioned proteins play a significant role in this process. In my novel me dication, I would include a unique chemical property that increased or decreased synaptic efficiency based on under or overexpression of these crucial pre-synaptic proteins. This would allow dopamine and glutamate levels to return to appropriate levels and hopefully allay symptoms of schizophrenia. Another potential aspect to myShow MoreRelatedSchizophrenia Research Paper1296 Words   |  6 PagesResearch Paper III I chose to write my research paper over Schizophrenia. It is a psychological disorder that I have always found fascinating. It is a serious disorder that consumes a persons life and is nearly impossible to control. 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I haveRead MoreThis Paper Will Discuss Different Aspects Of Schizophrenia.1841 Words   |  8 PagesThis paper will discuss different aspects of Schizophrenia. Schizophrenia is an illness that affects how a person thinks, feels, and acts. It affects each person differently both on a daily basis and over a lifetime. Living with schizophrenia may make it harder manage your feelings, think clearly and deal with other people on the daily basis. Many people who battle with this disorder have difficulty distinguishing between what is real and what is imaginary. Schizophrenics have a hard time in socialRead MorePsychiatric Treatment: Mental Disorders, Schizophrenia, and The Yellow Paper2081 Words   |  9 Pagesworld’s entire population, more than one percent of people have been diagnosed with schizophrenia (Brain and Behavior Research Foundation). When thinking of the billions of people in the world, it might not seem like that many people but once the number of those diagnosed i s calculated it seems much larger. Currently there are more than seventy million people in the world that have been diagnosed with schizophrenia, only diagnosed. There are probably several more people who have this disorder andRead MoreA Research Paper on Schizophrenia984 Words   |  4 PagesSchizophrenia Introduction Schizophrenia is a severe, disabling and chronic disorder that affects people. Schizophrenia is diagnosed as a psychotic disorder. This is because a person suffering from schizophrenia cannot tell their own thoughts, perceptions, ideas, and imaginations from the reality. There is continuing debate and research as to whether schizophrenia is one condition or a combination of more than one syndrome that have related features. People suffering from schizophrenia may seemRead MoreSchizophrenia Research Paper1781 Words   |  8 Pagespeople dealing with schizophrenia? Throughout the years people with schizophrenia has dealt with different type of treatments, exorcism, insulin shock, electroconvulsive therapy, lobotomy, and fever therapy. Schizophrenia is a chronic, severe, and disabling mental disorder characterized by deficit in thought processes, perceptions and emotional responsiveness. It is a serious disorder on the mind and brain and it is also highly treatable. Although there is no cure for schizophrenia, treatment successRead MoreChildhood Trauma and Symptoms of Psychological Disorders Essay examples1567 Words   |  7 Pagesthe symptoms of patients with psychological disorders such as Schizophrenia and Psychosis, or can the trauma cause a patient to have Schizophrenia or Psychosis. Many case studies’ findings state that there is a link. Some studies say only certain symptoms are affected. I want to know what symptoms are affected and what kind of childhood trauma could have possibly affected the symptoms of patients who have been diagnosed with Schizophrenia and Psychosis, or if the childhood trauma could have caused